Active Flows Cluster Cell Surface Proteins

proteomics study of polyethylenimine interaction with cell surface proteins in human colon adenocarcinoma cell line

ADP-Ribosylation of T Cell Surface Proteins

Cell-surface engineering with GPI-anchored proteins.

Protein engineering of cell surfaces is a potentially powerful technology through which the surface protein composition of cells can be manipulated without gene transfer. This technology exploits the fact that proteins that are anchored by glycoinositol phospholipids (GPIs), when purified and added to cells in vitro, incorporate into their surface membranes and are fully functional. By substitu...

Modular proteins at the cell surface.

Many proteins, including cell-surface receptors, extracellular matrix (ECM) proteins and intracellular signalling systems, are constructed from a relatively small number of domains or modules. Modularity provides biological systems with a convenient way of presenting binding sites on a stable protein scaffold, in the correct position for function; it also allows regulation by module rearrangeme...

Metabolic Release of Cell Surface Proteins

The proliferation and differentiation of 1)maphoid cells can be stimulated bv specific antigens, antigen-antibody complexes, plant mitogens and hormones. The initial event in the response to these diverse agents is believed to be the binding of stimulator molecules to receptors located on the cell surface (1, 2). However, the mechanism by which the binding of receptor to its ligand triggers cel...